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The end of resistance primarily concerns the nitroimidazoles metronidazole or tinidazole and macro lides clarithromycin 38, 39 .

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The recommended dose in non-pregnant females is a 2 g oral dose once daily for 2 days taken with food or a 1 g oral dose once daily for 5 days taken with foodThe use of tinidazole in pregnant patients has not been studied for bacterial vaginosis.

Tinidazole is indicated for the treatment of intestinal amebiasis and amebic liver abscess caused by Entamoeba histolytica in both adults and pediatric patients older than three years of ageIt is not indicated in the treatment of asymptomatic cyst passagesee Clinical Studies

Keep all appointments with your doctor and the laboratoryYour doctor may order certain lab tests to check your body’s response to tinidazoleBefore having any laboratory testtell your doctor and the laboratory personnel that you are taking tinidazole.

It is advisable to take tinidazole with food to minimize the incidence of epigastric discomfort and other gastrointestinal side-effectsFood does not affect the oral bioavailability of tinidazolesee CLINICAL PHARMACOLOGY

The most common adverse reactions in treated patientsincidence2which were not identified in the trichomoniasisgiardiasis and amebiasis studiesare gastrointestinaldecreased appetiteand flatulencerenalurinary tract infectionpainful urinationand urine abnormalityand other reactions including pelvic painvulvo-vaginal discomfortvaginal odormenorrhagiaand upper respiratory tract infectionSee Clinical Studies

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